Impact of prenatal and childhood adversity effects around World War II on multimorbidity: results from the KORA-Age study.

ABSTRACT:

Background

While risk factors for age-related diseases may increase multimorbidity (MM), early life deprivation may also accelerate the development of chronic diseases and MM.

Methods

This study explores the prevalence and pattern of MM in 65-71 year-old individuals born before, during, and after World War II in Southern Germany based on two large cross-sectional KORA (Cooperative Health Research in the Region of Augsburg) -Age studies in 2008/9 and 2016. MM was defined as having at least two chronic diseases, and birth periods were classified into five phases: pre-war, early war, late war, famine, and after the famine period. Logistic regression models were used to analyze the effect of the birth phases on MM with adjustment for sociodemographic and lifestyle risk factors.

SUBMITTER: Arshadipour A 

PROVIDER: S-EPMC8832818 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature