High male specific contribution of the X-chromosome to individual global recombination rate in dairy cattle.

ABSTRACT:

Background

Meiotic recombination plays an important role in reproduction and evolution. The individual global recombination rate (GRR), measured as the number of crossovers (CO) per gametes, is a complex trait that has been shown to be heritable. The sex chromosomes play an important role in reproduction and fertility related traits. Therefore, variants present on the X-chromosome might have a high contribution to the genetic variation of GRR that is related to meiosis and to reproduction.

Results

We herein used genotyping data from 58,474 New Zealand dairy cattle to estimate the contribution of the X-chromosome to male and female GRR levels. Based on the pedigree-based relationships, we first estimated that the X-chromosome accounted for 30% of the total additive genetic va

SUBMITTER: Kadri NK 

PROVIDER: S-EPMC8832838 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature