Diagnosing Vitreoretinal Lymphomas-An Analysis of the Sensitivity of Existing Tools.

ABSTRACT: Vitreoretinal lymphoma (VRL) is a rare ocular pathology that is notorious for mimicking chronic uveitis, which is a seemingly benign condition in comparison. The most common form of VRL is the diffuse large B-cell type, and there has been a high mortality rate. This dismal prognosis can be improved significantly if the disease is diagnosed early, but until now there is no consensus on an appropriate diagnostic algorithm. We conducted a retrospective search of PubMed Central® and analyzed results from thirty-three studies that were published between 2011-2021. The chosen studies incorporated some popular testing tools for VRL, and our analyses focused on comparing the average sensitivity of five diagnostic methods. The methods included cytology including ancillary immunohistochemistry, Myel

SUBMITTER: Sehgal A 

PROVIDER: S-EPMC8833443 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature