Comparative Proteomics Study of Yak Milk from Standard and Naturally Extended Lactation Using iTRAQ Technique.

ABSTRACT: Extended lactation is a common phenomenon in lactating yaks under grazing and natural reproduction conditions. To elucidate differences in milk protein compositions and mammary gland functions between yaks of standard lactation (TL yaks) and prolonged lactation (HL yaks), whole milk samples of TL yaks and HL yaks (n = 15 each) were collected from a yak pasture at the northwest highland of China. The iTRAQ technique was used to compare the skim milk proteins in the two yak groups. A total of 202 differentially expressed proteins (DEPs) were revealed, among which 109 proteins were up-regulated and 93 were down-regulated in the milk of HL yaks compared to TL yaks. Caseins including κ-casein, αs1-casein, αs2-casein, and β-casein were up-regulated in HL yak milk over 1.43-fold. The GO function

SUBMITTER: Cao M 

PROVIDER: S-EPMC8833776 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature