Recombinant Tropomyosin from the Pacific Oyster (Crassostrea gigas) for Better Diagnosis.

ABSTRACT: The Pacific oyster is a commercially important mollusc and, in contrast to most other shellfish species, frequently consumed without prior heat treatment. Oysters are rich in many nutrients but can also cause food allergy. Knowledge of their allergens and cross-reactivity remains very limited. These limitations make an optimal diagnosis of oyster allergy difficult, in particular to the Pacific oyster (Crassostrea gigas), the most cultivated and consumed oyster species worldwide. This study aimed to characterise IgE sensitisation profiles of 21 oyster-sensitised patients to raw and heated Pacific oyster extract using immunoblotting and advanced mass spectrometry, and to assess the relevance of recombinant oyster allergen for improved diagnosis. Tropomyosin was identified as the major allerg

SUBMITTER: Nugraha R 

PROVIDER: S-EPMC8834279 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature