Intraductal Carcinoma of the Prostate as a Cause of Prostate Cancer Metastasis: A Molecular Portrait.
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ABSTRACT:
SUBMITTER: Pantazopoulos H
PROVIDER: S-EPMC8834356 | biostudies-literature | 2022 Feb
REPOSITORIES: biostudies-literature
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Intraductal Carcinoma of the Prostate as a Cause of Prostate Cancer Metastasis: A Molecular Portrait.
Pantazopoulos Helen H Diop Mame-Kany MK Grosset Andrée-Anne AA Rouleau-Gagné Frédérique F Al-Saleh Afnan A Boblea Teodora T Trudel Dominique D
Cancers 20220206 3
Intraductal carcinoma of the prostate (IDC-P) is one of the most aggressive types of prostate cancer (PCa). IDC-P is identified in approximately 20% of PCa patients and is associated with recurrence, metastasis, and PCa-specific death. The main feature of this histological variant is the colonization of benign glands by PCa cells. Although IDC-P is a well-recognized independent parameter for metastasis, mechanisms by which IDC-P cells can spread and colonize other tissues are not fully known. In ...[more]
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