Disease-Related Risk Factors for Caregiver Burden among Family Caregivers of Persons with Schizophrenia: A Systematic Review and Meta-Analysis.

ABSTRACT: This study aimed to conduct a quantitative synthesis of the clinical correlates of caregiver burden in schizophrenia studies published in the last two decades. Derived from eight electronic databases, this meta-analytic review revisits 34 English articles published from 2000 to 2020 relevant to family caregiver burden in the schizophrenia field. The Newcastle-Ottawa Scale (NOS) was used to assess study quality. The pooled effect sizes of the selected studies ranged from -0.390 to 0.751. The results indicated a significant association between a heavier burden and disease-related risk factors, including more severe symptoms, greater general psychopathology, greater severity of functional impairment, and longer duration of illness. The results show moderating effects of study characteristics

SUBMITTER: Peng MM 

PROVIDER: S-EPMC8835439 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature