Prenatal exposure to metal mixtures and newborn neurobehavior in the Rhode Island Child Health Study.

ABSTRACT:

Background

Prenatal exposure to metals can affect the developing fetus and negatively impact neurobehavior. The associations between individual metals and neurodevelopment have been examined, but little work has explored the potentially detrimental neurodevelopmental outcomes associated with the combined impact of coexisting metals. The objective of this study is to evaluate prenatal metal exposure mixtures in the placenta to elucidate the link between their combined effects on newborn neurobehavior.

Method

This study included 192 infants with available placental metal and NICU Network Neurobehavioral Scale data at 24 hours-72 hours age. Eight essential and nonessential metals (cadmium, cobalt, copper, iron, manganese, molybdenum, selenium, zinc) detected in more than 80% of

SUBMITTER: Tung PW 

PROVIDER: S-EPMC8835549 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature