Model of Genetic Code Structure Evolution under Various Types of Codon Reading.

ABSTRACT: The standard genetic code (SGC) is a set of rules according to which 64 codons are assigned to 20 canonical amino acids and stop coding signal. As a consequence, the SGC is redundant because there is a greater number of codons than the number of encoded labels. This redundancy implies the existence of codons that encode the same genetic information. The size and organization of such synonymous codon blocks are important characteristics of the SGC structure whose evolution is still unclear. Therefore, we studied possible evolutionary mechanisms of the codon block structure. We conducted computer simulations assuming that coding systems at early stages of the SGC evolution were sets of ambiguous codon assignments with high entropy. We included three types of reading systems characterized by

SUBMITTER: Blazej P 

PROVIDER: S-EPMC8835785 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature