Ontology highlight
ABSTRACT:
SUBMITTER: Zumaya ALV
PROVIDER: S-EPMC8835878 | biostudies-literature | 2022 Jan
REPOSITORIES: biostudies-literature
Zumaya Alma Lucia Villela ALV Rimpelová Silvie S Štějdířová Markéta M Ulbrich Pavel P Vilčáková Jarmila J Hassouna Fatima F
International journal of molecular sciences 20220121 3
Anti-CD133 monoclonal antibody (Ab)-conjugated poly(lactide-co-glycolide) (PLGA) nanocarriers, for the targeted delivery of oxaliplatin (OXA) and superparamagnetic nanoparticles (IO-OA) to colorectal cancer cells (CaCo-2), were designed, synthesized, characterized, and evaluated in this study. The co-encapsulation of OXA and IO-OA was achieved in two types of polymeric carriers, namely, PLGA and poly(lactide-co-glycolide)-poly(ethylene glycol) (PLGA-PEG) by double emulsion. PLGA_IO-OA_OXA and PE ...[more]