Improving Protein Quantity and Quality-The Next Level of Plant Molecular Farming.

ABSTRACT: Plants offer several unique advantages in the production of recombinant pharmaceuticals for humans and animals. Although numerous recombinant proteins have been expressed in plants, only a small fraction have been successfully put into use. The hugely distinct expression systems between plant and animal cells frequently cause insufficient yield of the recombinant proteins with poor or undesired activity. To overcome the issues that greatly constrain the development of plant-produced pharmaceuticals, great efforts have been made to improve expression systems and develop alternative strategies to increase both the quantity and quality of the recombinant proteins. Recent technological revolutions, such as targeted genome editing, deconstructed vectors, virus-like particles, and humanized glyc

SUBMITTER: Liu H 

PROVIDER: S-EPMC8836236 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature