Genome-Wide Prediction of Transcription Start Sites in Conifers.

ABSTRACT: The identification of promoters is an essential step in the genome annotation process, providing a framework for gene regulatory networks and their role in transcription regulation. Despite considerable advances in the high-throughput determination of transcription start sites (TSSs) and transcription factor binding sites (TFBSs), experimental methods are still time-consuming and expensive. Instead, several computational approaches have been developed to provide fast and reliable means for predicting the location of TSSs and regulatory motifs on a genome-wide scale. Numerous studies have been carried out on the regulatory elements of mammalian genomes, but plant promoters, especially in gymnosperms, have been left out of the limelight and, therefore, have been poorly investigated. The aim

SUBMITTER: Bondar EI 

PROVIDER: S-EPMC8836283 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature