Test-trace-isolate-quarantine (TTIQ) intervention strategies after symptomatic COVID-19 case identification.

ABSTRACT: The test-trace-isolate-quarantine (TTIQ) strategy, where confirmed-positive pathogen carriers are isolated from the community and their recent close contacts are identified and pre-emptively quarantined, is used to break chains of transmission during a disease outbreak. The protocol is frequently followed after an individual presents with disease symptoms, at which point they will be tested for the pathogen. This TTIQ strategy, along with hygiene and social distancing measures, make up the non-pharmaceutical interventions that are utilised to suppress the ongoing COVID-19 pandemic. Here we develop a tractable mathematical model of disease transmission and the TTIQ intervention to quantify how the probability of detecting and isolating a case following symptom onset, the fraction of contact

SUBMITTER: Ashcroft P 

PROVIDER: S-EPMC8836351 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature