Pulmonary Tuberculosis and Risk of Lung Cancer: A Systematic Review and Meta-Analysis.

ABSTRACT: Pulmonary tuberculosis (TB) is a known risk factor for lung cancer. However, a detailed analysis of lung cancer type, age, sex, smoking, and TB burden associated with geographic and socioeconomic status has not been performed previously. We systematically appraised relevant observational studies reporting an association between pulmonary TB and lung cancer. All studies were included in the primary analysis, and studies that used robust TB diagnostic methods, such as validated medical diagnostic codes, were included in the secondary analysis. Thirty-two articles were included. The association between the history of pulmonary TB and diagnosis of lung cancer was statistically significant (OR 2.09, 95% CI: 1.62-2.69, p < 0.001). There was a high heterogeneity (I2 = 95%), without any publicatio

SUBMITTER: Hwang SY 

PROVIDER: S-EPMC8836400 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature