Predictive roles of D-dimer for mortality of patients with community-acquired pneumonia: a systematic review and meta-analysis.

ABSTRACT:

Objective

To explore the predictive roles of D-dimer for the mortality of patients with community-acquired pneumonia (CAP).

Methods

This was a systematic review and meta-analysis. We searched the following databases: PubMed, EMBASE, Web of Science, Ovid MEDLINE, and Cochrane Library from their inception to July 26, 2020. Studies exploring the relationship between blood D-dimer levels and CAP-related mortality were selected. In this meta-analysis, we calculated mortality rates, sensitivity, specificity, positive likelihood ratios, and negative likelihood ratios.

Results

The search identified 1,073 articles, 8 of which (a total of 2,126 patients) were included in this meta-analysis. The pooled mortality rate of the overall sample was 0.10 (95% CI, 0.08-0.14). The levels

SUBMITTER: Yang C 

PROVIDER: S-EPMC8836614 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature