Interactions between Radiation and One-Carbon Metabolism.

ABSTRACT: Metabolic reprogramming is a hallmark of cancer. Cancer cells rewire one-carbon metabolism, a central metabolic pathway, to turn nutritional inputs into essential biomolecules required for cancer cell growth and maintenance. Radiation therapy, a common cancer therapy, also interacts and alters one-carbon metabolism. This review discusses the interactions between radiation therapy, one-carbon metabolism and its component metabolic pathways.

SUBMITTER: Korimerla N 

PROVIDER: S-EPMC8836916 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature