Associated Factors of High Sedative Requirements within Patients with Moderate to Severe COVID-19 ARDS.

ABSTRACT: The coronavirus pandemic continues to challenge global healthcare. Severely affected patients are often in need of high doses of analgesics and sedatives. The latter was studied in critically ill coronavirus disease 2019 (COVID-19) patients in this prospective monocentric analysis. COVID-19 acute respiratory distress syndrome (ARDS) patients admitted between 1 April and 1 December 2020 were enrolled in the study. A statistical analysis of impeded sedation using mixed-effect linear regression models was performed. Overall, 114 patients were enrolled, requiring unusual high levels of sedatives. During 67.9% of the observation period, a combination of sedatives was required in addition to continuous analgesia. During ARDS therapy, 85.1% (n = 97) underwent prone positioning. Veno-venous

SUBMITTER: Flinspach AN 

PROVIDER: S-EPMC8837042 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature