Alcohol use in emerging adults associated with lower rich-club connectivity and greater connectome network disorganization.

ABSTRACT:

Background

Emerging adulthood is a critical neurodevelopmental stage, with alcohol use during this period consistently associated with brain abnormalities and damage in anatomical structure and white matter integrity. However, it is less clear how alcohol use is associated with the brain's structural organization (i.e., white matter connections between anatomical regions). Recent connectome research has focused on rich-club regions, a collection of highly-interconnected hubs that are critical in brain communication and global network organization and disproportionately vulnerable to insults.

Methods

For the first time, we examined alcohol use associations with structural rich-club and connectome organization in emerging adults (N = 66).

Results

Greater lifetime drinks

SUBMITTER: Hua JPY 

PROVIDER: S-EPMC8837437 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature