Comparison of ⁶⁸Ga-PSMA PET/CT and multiparametric MRI for the detection of low- and intermediate-risk prostate cancer.

ABSTRACT:

Purpose

To assess ⁶⁸Ga-PSMA PET/CT for detection of low- and intermediate-risk prostate cancer (PCa), high-risk PCa in comparison with mpMRI, respectively, and to determine which of low- and intermediate-risk PCa are more likely to be detected by ⁶⁸Ga-PSMA PET/CT.

Methods

We conducted a retrospective analysis of patients who had undergone a prostate biopsy and/or radical prostatectomy and who were scanned with ⁶⁸Ga-PSMA PET/CT and mpMRI between June 2019 and March 2021. The mpMRI images were scored with the Prostate Imaging-Reporting and Data System Version 2.1 (PI-RADS) and were classified as either negative (PI-RADS 1-3) or positive (PI-RADS 4-5). Suspicious ⁶⁸Ga-PSMA PET/CT lesions were reviewed for each relevant patient and cla

SUBMITTER: Zhou C 

PROVIDER: S-EPMC8837766 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature