PEBP balances apoptosis and autophagy in whitefly upon arbovirus infection.
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ABSTRACT:
SUBMITTER: Wang S
PROVIDER: S-EPMC8837789 | biostudies-literature | 2022 Feb
REPOSITORIES: biostudies-literature
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PEBP balances apoptosis and autophagy in whitefly upon arbovirus infection.
Wang Shifan S Guo Huijuan H Zhu-Salzman Keyan K Ge Feng F Sun Yucheng Y
Nature communications 20220211 1
Apoptosis and autophagy are two common forms of programmed cell death (PCD) used by host organisms to fight against virus infection. PCD in arthropod vectors can be manipulated by arboviruses, leading to arbovirus-vector coexistence, although the underlying mechanism is largely unknown. In this study, we find that coat protein (CP) of an insect-borne plant virus TYLCV directly interacts with a phosphatidylethanolamine-binding protein (PEBP) in its vector whitefly to downregulate MAPK signaling c ...[more]
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