Prenatal and Postnatal Choline Supplementation in Fetal Alcohol Spectrum Disorder.

ABSTRACT: Fetal alcohol spectrum disorder (FASD) is common and represents a significant public health burden, yet very few interventions have been tested in FASD. Cognitive deficits are core features of FASD, ranging from broad intellectual impairment to selective problems in attention, executive functioning, memory, visual-perceptual/motor skills, social cognition, and academics. One potential intervention for the cognitive impairments associated with FASD is the essential nutrient choline, which is known to have numerous direct effects on brain and cognition in both typical and atypical development. We provide a summary of the literature supporting the use of choline as a neurodevelopmental intervention in those affected by prenatal alcohol. We first discuss how alcohol interferes with normal brai

SUBMITTER: Ernst AM 

PROVIDER: S-EPMC8837993 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature