Probiotic Consumption Boosts Thymus in Obesity and Senescence Mouse Models.

ABSTRACT: The ability of the immune system to respond to different pathogens throughout life requires the constant production and selection of T cells in the thymus. This immune organ is very sensitive to age, infectious processes and nutrition disorders (obesity and malnutrition). Several studies have shown that the incorporation of some probiotic bacteria or probiotic fermented milk in the diet has beneficial effects, not only at the intestinal level but also on distant mucosal tissues, improving the architecture of the thymus in a malnutrition model. The aim of the present study was to determine whether supplementation with the probiotic strain Lactobacillus casei CRL 431 and/or its cell wall could improve body weight, intestinal microbiota and thymus structure and function in both obese and agin

SUBMITTER: Balcells F 

PROVIDER: S-EPMC8838891 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature