Novel 3D Bioglass Scaffolds for Bone Tissue Regeneration.

ABSTRACT: The design of scaffolds with optimal biomechanical properties for load-bearing applications is an important topic of research. Most studies have addressed this problem by focusing on the material composition and not on the coupled effect between the material composition and the scaffold architecture. Polymer-bioglass scaffolds have been investigated due to the excellent bioactivity properties of bioglass, which release ions that activate osteogenesis. However, material preparation methods usually require the use of organic solvents that induce surface modifications on the bioglass particles, compromising the adhesion with the polymeric material thus compromising mechanical properties. In this paper, we used a simple melt blending approach to produce polycaprolactone/bioglass pellets to con

SUBMITTER: Daskalakis E 

PROVIDER: S-EPMC8839207 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature