PH-Induced 3D Printable Chitosan Hydrogels for Soft Actuation.

ABSTRACT: Three-dimensional (3D) printing represents a suitable technology for the development of biomimetic scaffolds for biomedical and tissue engineering applications. However, hydrogel-based inks' printability remains a challenge due to their restricted print accuracy, mechanical properties, swelling or even cytotoxicity. Chitosan is a natural-derived polysaccharide that has arisen as a promising bioink due to its biodegradability, biocompatibility, sustainability and antibacterial properties, among others, as well as its ability to form hydrogels under the influence of a wide variety of mechanisms (thermal, ionic, pH, covalent, etc.). Its poor solubility at physiological pH, which has traditionally restricted its use, represents, on the contrary, the simplest way to induce chitosan gelation. Ac

SUBMITTER: Maiz-Fernandez S 

PROVIDER: S-EPMC8839485 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature