Hydrogen Bonding and Polymorphism of Amino Alcohol Salts with Quinaldinate: Structural Study.

ABSTRACT: Three amino alcohols, 3-amino-1-propanol (abbreviated as 3a1pOH), 2-amino-1-butanol (2a1bOH), and 2-amino-2-methyl-1-propanol (2a2m1pOH), were reacted with quinoline-2-carboxylic acid, known as quinaldinic acid. This combination yielded three salts, (3a1pOHH)quin (1, 3a1pOHH+ = protonated 3-amino-1-propanol, quin- = anion of quinaldinic acid), (2a1bOHH)quin (2, 2a1bOHH+ = protonated 2-amino-1-butanol), and (2a2m1pOHH)quin (3, 2a2m1pOHH+ = protonated 2-amino-2-methyl-1-propanol). The 2-amino-1-butanol and 2-amino-2-methyl-1-propanol systems produced two polymorphs each, labeled 2a/2b and 3a/3b, respectively. The compounds were characterized by X-ray structure analysis on single-crystal. The crystal structures of all consisted of protonated amino alcohols with NH3+ moiety and quinaldinate an

SUBMITTER: Podjed N 

PROVIDER: S-EPMC8839704 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature