Ontology highlight
ABSTRACT: Objectives
To evaluate host factors associated with the risk of coronavirus disease 2019 (COVID-19) pneumonia in vaccinated adults.Methods
A cohort study was conducted in Mexico, and data from 1607 adults with confirmed illness, with a positive history of COVID-19 vaccination, were analyzed. Risk ratios (RR) and 95% confidence intervals (CI) were computed as a measure of the significance of the associations between putative risk factors and the prevalence of COVID-19 pneumonia in vaccinated subjects.Results
The overall risk of pneumonia was 1.98 per 1000 person-days. In the multiple regression analysis, older subjects, those with a history of smoking (current), obesity, and type 2 diabetes mellitus were at increased risk of pneumonia.Conclusions
Our results suggest that the effectiveness of COVID-19 vaccines may be reduced in a subset of adults who are older aged, smokers, obese, or have type 2 diabetes mellitus.
SUBMITTER: Murillo-Zamora E
PROVIDER: S-EPMC8839797 | biostudies-literature | 2022 May
REPOSITORIES: biostudies-literature
Murillo-Zamora Efrén E Sánchez-Piña Ramón Alberto RA Trujillo Xóchitl X Huerta Miguel M Ríos-Silva Mónica M Mendoza-Cano Oliver O
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 20220212
<h4>Objectives</h4>To evaluate host factors associated with the risk of coronavirus disease 2019 (COVID-19) pneumonia in vaccinated adults.<h4>Methods</h4>A cohort study was conducted in Mexico, and data from 1607 adults with confirmed illness, with a positive history of COVID-19 vaccination, were analyzed. Risk ratios (RR) and 95% confidence intervals (CI) were computed as a measure of the significance of the associations between putative risk factors and the prevalence of COVID-19 pneumonia in ...[more]