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Independent risk factors of COVID-19 pneumonia in vaccinated Mexican adults.


ABSTRACT:

Objectives

To evaluate host factors associated with the risk of coronavirus disease 2019 (COVID-19) pneumonia in vaccinated adults.

Methods

A cohort study was conducted in Mexico, and data from 1607 adults with confirmed illness, with a positive history of COVID-19 vaccination, were analyzed. Risk ratios (RR) and 95% confidence intervals (CI) were computed as a measure of the significance of the associations between putative risk factors and the prevalence of COVID-19 pneumonia in vaccinated subjects.

Results

The overall risk of pneumonia was 1.98 per 1000 person-days. In the multiple regression analysis, older subjects, those with a history of smoking (current), obesity, and type 2 diabetes mellitus were at increased risk of pneumonia.

Conclusions

Our results suggest that the effectiveness of COVID-19 vaccines may be reduced in a subset of adults who are older aged, smokers, obese, or have type 2 diabetes mellitus.

SUBMITTER: Murillo-Zamora E 

PROVIDER: S-EPMC8839797 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature

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Publications

Independent risk factors of COVID-19 pneumonia in vaccinated Mexican adults.

Murillo-Zamora Efrén E   Sánchez-Piña Ramón Alberto RA   Trujillo Xóchitl X   Huerta Miguel M   Ríos-Silva Mónica M   Mendoza-Cano Oliver O  

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 20220212


<h4>Objectives</h4>To evaluate host factors associated with the risk of coronavirus disease 2019 (COVID-19) pneumonia in vaccinated adults.<h4>Methods</h4>A cohort study was conducted in Mexico, and data from 1607 adults with confirmed illness, with a positive history of COVID-19 vaccination, were analyzed. Risk ratios (RR) and 95% confidence intervals (CI) were computed as a measure of the significance of the associations between putative risk factors and the prevalence of COVID-19 pneumonia in  ...[more]

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