The Effect of the Ketogenic Diet on Adiponectin, Omentin and Vaspin in Children with Drug-Resistant Epilepsy.

ABSTRACT:

Background

Changes in adipokine secretion may be involved in the anti-epileptic effect of a ketogenic diet (KD) in drug-resistant epilepsy (DRE).

Objectives

The assessment of the influence of KD on serum adiponectin, omentin-1, and vaspin in children with DRE.

Methods

Anthropometric measurements (weight, height, BMI, and waist-to-hip circumference ratio) were performed in 72 children aged 3-9 years, divided into 3 groups: 24 children with DRE treated with KD, 26-treated with valproic acid (VPA), and a control group of 22 children. Biochemical tests included fasting glucose, insulin, beta-hydroxybutyric acid, lipid profile, aminotransferases activities, and blood gasometry. Serum levels of adiponectin, omentin-1 and vaspin were assayed using commercially available ELIS

SUBMITTER: Chyra M 

PROVIDER: S-EPMC8839826 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature