Prospective Multicenter Comparison of Open and Robotic Radical Prostatectomy: The PROST-QA/RP2 Consortium.

ABSTRACT:

Purpose

Our goal was to evaluate the comparative effectiveness of robot-assisted laparoscopic prostatectomy (RALP) and open radical prostatectomy (ORP) in a multicenter study.

Materials and methods

We evaluated men with localized prostate cancer at 11 high-volume academic medical centers in the United States from the PROST-QA (2003-2006) and the PROST-QA/RP2 cohorts (2010-2013) with a pre-specified goal of comparing RALP (549) and ORP (545). We measured longitudinal patient-reported health-related quality of life (HRQOL) at pre-treatment and at 2, 6, 12, and 24 months, and pathological and perioperative outcomes/complications.

Results

Demographics, cancer characteristics, and margin status were similar between surgical approaches. ORP subjects were more likely to unde

SUBMITTER: Chang P 

PROVIDER: S-EPMC8840795 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature