The risk of childhood brain tumors associated with delivery interventions: A Danish matched case-control study.

ABSTRACT:

Background

Head trauma has been associated with increased brain tumor risk in adults. Instrument assisted delivery can be a cause of head trauma in newborns. The goal of this study was to determine if instrument-assisted deliveries influenced the odds of childhood brain tumors in Denmark.

Methods

We conducted a matched case-control study of childhood (<20 years) brain tumors in Denmark born between 1978 and 2013 and diagnosed 1978-2016. A total of 1678 brain tumor cases were identified and 25 controls were matched to each case based on the child's sex and birth date (N = 40,934). Conditional logistic regression was used to estimate effects (odds ratios (OR) and 95% confidence intervals (95%CI)) for variables of interest.

Results

Compared to children birthed by spontan

SUBMITTER: Yeh KW 

PROVIDER: S-EPMC8840805 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature