Candida periprosthetic joint infections - risk factors and outcome between albicans and non-albicans strains.

ABSTRACT:

Background

Despite its scarcity, fungal periprosthetic joint infection (PJI) is of great clinical relevance as diagnosis and treatment are highly challenging. Previous analyses focused on the treatment rather than the role of the causative fungal agent on clinical outcome. This is the largest study of its kind to evaluate Candida strain-dependent differences in patients with fungal PJI.

Methods

We retrospectively analyzed 29 patients who underwent surgical intervention due to Candida hip or knee PJI in our department from 2010 to 2018. PJI was defined according to IDSA, recurrent PJI according to modified Delphi consensus criteria. Statistical analysis was performed using t-test, chi-square test with Yates correction, and log rank test.

Results

Besides age and affecte

SUBMITTER: Karczewski D 

PROVIDER: S-EPMC8840907 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature