Trauma Characteristics Moderate the Relation Between Estradiol and Trauma-Related Symptoms.

ABSTRACT: Women are more likely to develop posttraumatic stress disorder (PTSD) than men, and fluctuations in gonadal hormones might contribute to this vulnerability. Low-estradiol states are associated with aversive affective experiences, including trauma-related symptoms. However, the impact of trauma characteristics on the relation between estradiol and trauma-related symptoms is unknown. We used a clinical interview and 10-day ecological momentary assessment (EMA) that spanned low- and high-estradiol menstrual cycle phases to test trauma type, chronicity, and timing as moderators of the association between estradiol and trauma-related symptoms in 40 naturally cycling young women. We tested interactions between trauma characteristics and (a) estradiol on self-reported symptoms and (b) menstrual c

SUBMITTER: Rieder JK 

PROVIDER: S-EPMC8840997 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature