Ontology highlight
ABSTRACT:
SUBMITTER: Uwamino Y
PROVIDER: S-EPMC8841208 | biostudies-literature | 2022 Mar
REPOSITORIES: biostudies-literature
Uwamino Yoshifumi Y Yokoyama Takashi T Shimura Takako T Nishimura Tomoyasu T Sato Yasunori Y Wakui Masatoshi M Kosaki Kenjiro K Hasegawa Naoki N Murata Mitsuru M
Vaccine 20220214 13
The reduced vaccine efficacy against the SARS-CoV-2 variant lineage B. 1.351 (beta variant) containing the E484K and N501Y mutations is well known. The E484K mutation in SARS-CoV-2 is thought to be responsible for weakened humoral immunity. Vaccine efficacy against the R.1 lineage, which contains the E484K mutation but not the N501Y mutation, is uncertain. Serum samples were collected from 100 healthy Japanese participants three weeks after receiving the second dose of the BNT162b2 vaccine, and ...[more]