Association Between Cholecystectomy and Gastric Cancer Risk: A Systematic Review and Meta-Analysis.

ABSTRACT:

Objectives

Although several epidemiological studies have attempted to evaluate the relationship between cholecystectomy and gastric cancer risk, the findings have been controversial. This study aimed to carry out a systematic review and meta-analysis following the reporting guidelines to comprehensively analyze and quantify the evidence of the aforementioned association.

Methods

Studies were identified by searching the Medline (PubMed), Embase, and Web of Science from inception to November 30, 2020, with only studies published in English being considered. Summary relative risks (RRs) and 95% confidence intervals (CIs) were calculated by random-effects models.

Results

Eight studies (five cohort studies and three case-control studies) with a total of 26,063 gastric canc

SUBMITTER: Yang Y 

PROVIDER: S-EPMC8841561 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature