Focal Radiotherapy of Brain Metastases in Combination With Immunotherapy and Targeted Drug Therapy.

ABSTRACT: Advances in systemic treatment and in brain imaging have led to a higher incidence of diagnosed brain metastases. In the treatment of brain metastases, stereotactic radiotherapy and radiosurgery, systemic immunotherapy, and targeted drug therapy are important evidence-based options. In this review, we summarize the available evidence on the treatment of brain metastases of the three main types of cancer that give rise to them: non-small-cell lung cancer, breast cancer, and malignant melanoma. This narrative review is based on pertinent original articles, meta-analyses, and systematic reviews that were retrieved by a selective search in PubMed. These publications were evaluated and discussed by an expert panel including radiation oncologists, neurosurgeons, and oncologists. There have not y

SUBMITTER: Kaul D 

PROVIDER: S-EPMC8841640 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature