Prognostic Implications of a Second Peak of High-Sensitivity Troponin T After Myocardial Infarction.

ABSTRACT:

Background

After an acute myocardial infarction (MI), repeated measurement of cardiac biomarkers is commonly performed, although not recommended in current guidelines. There is only limited data on the kinetics of troponin in this phase. For high-sensitivity cardiac troponin T (hs-cTnT), but not high-sensitivity cardiac troponin I (hs-cTnI), late increases in terms of a second peak have been described. Their impact on the prognosis of patients with MI remains unclear.

Methods

We included 2,305 patients presenting to the emergency department with symptoms suggestive of MI. Five hundred and seven were diagnosed with MI. Hs-cTnT, creatine kinase (CK) and the MB fraction of CK (CK-MB) were measured at admission, after 1 and 3 h and thereafter as indicated by the treating physici

SUBMITTER: Hartikainen TS 

PROVIDER: S-EPMC8841767 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature