Clinical practice guideline recommendations on tapering and discontinuing antidepressants for depression: a systematic review.

ABSTRACT:

Background

Tapering and discontinuing antidepressants are important aspects of the management of patients with depression and should therefore be considered in clinical practice guidelines.

Objectives

We aimed to assess the extent and content, and appraise the quality, of guidance on tapering and discontinuing antidepressants in major clinical practice guidelines on depression.

Methods

Systematic review of clinical practice guidelines on depression issued by national health authorities and major national or international professional organisations in the United Kingdom, the United States, Canada, Australia, Singapore, Ireland and New Zealand (PROSPERO CRD42020220682). We searched PubMed, 14 guideline registries and the websites of relevant organisations (last search 2

SUBMITTER: Sorensen A 

PROVIDER: S-EPMC8841913 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature