Factors influencing the statistical planning, design, conduct, analysis and reporting of trials in health care: A systematic review.

ABSTRACT:

Background

Trials in health care are prospective human research studies designed to test the effectiveness and safety of health care interventions, such as medications, surgeries, medical devices and other treatment or prevention interventions. Statistics is an important and powerful tool in trials. Inappropriately designed trials and/or inappropriate statistical analysis produce unreliable results and a lack of transparency when reported, with limited clinical use.

Aim

This systematic literature review aimed to identify, describe and synthesise factors contributing to or influencing the statistical planning, design, conduct, analysis and reporting of trials.

Methods

Information sources were retrieved from the following electronic citation databases: PubMed, Web of Sc

SUBMITTER: Zaki M 

PROVIDER: S-EPMC8842005 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature