Risk factors, management, and outcomes of Acanthamoeba keratitis: A retrospective analysis of 110 cases.

ABSTRACT:

Purpose

To evaluate the risk factors, medical and surgical management, and visual outcomes of patients affected by Acanthamoeba keratitis (AK) over a 16-year period.

Observations

Records were reviewed retrospectively for all AK patients treated at University of Iowa between 2002 and 2017. Main outcomes measured were risk factors, time to diagnosis, coinfection types, initial and final visual acuities, and treatment outcomes, with failure of medical therapy defined as need for therapeutic keratoplasty (TK). Effects of steroid use on these outcomes were determined. Among all AK cases occurring during the study period (N = 110), the median age of the AK cohort was 31 years (range 8-80 years), and 49.1% were men. Contact lens wear was the primary risk factor for AK (95/10

SUBMITTER: Scruggs BA 

PROVIDER: S-EPMC8842025 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature