Risk of chronic kidney disease in patients with obstructive sleep apnea.

ABSTRACT:

Study objectives

Chronic kidney disease (CKD) is a global health concern and a major risk factor for cardiovascular morbidity and mortality. Obstructive sleep apnea (OSA) may exacerbate this risk by contributing to the development of CKD. This study investigated the prevalence and patient awareness of the risk of CKD progression in individuals with OSA.

Methods

Adults referred to five Canadian academic sleep centers for suspected OSA completed a questionnaire, a home sleep apnea test or in-lab polysomnography and provided blood and urine samples for measurement of estimated glomerular filtration rate (eGFR) and the albumin:creatinine ratio (ACR), respectively. The risk of CKD progression was estimated from a heat map incorporating both eGFR and ACR.

Results

1295 adult

SUBMITTER: Beaudin AE 

PROVIDER: S-EPMC8842337 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature