Building Valveless Impedance Pumps From Biological Components: Progress and Challenges.

ABSTRACT: Valveless pumping based on Liebau mechanism entails asymmetrical positioning of the compression site relative to the attachment sites of the pump's elastic segment to the rest of the circuit. Liebau pumping is believed to play a key role during heart development and be involved in several other physiological processes. Until now studies of Liebau pump have been limited to numerical analyses, in silico modeling, experiments using non-biological elements, and a few indirect in vivo measurements. This review aims to stimulate experimental efforts to build Liebau pumps using biologically compatible materials in order to encourage further exploration of the fundamental mechanisms behind valveless pumping and its role in organ physiology. The covered topics include the biological o

SUBMITTER: Sarvazyan N 

PROVIDER: S-EPMC8842681 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature