Neuroanatomical correlates of speech and singing production in chronic post-stroke aphasia.

ABSTRACT: A classical observation in neurology is that aphasic stroke patients with impairments in speech production can nonetheless sing the same utterances. This preserved ability suggests a distinctive neural architecture for singing that could contribute to speech recovery. However, to date, these structural correlates remain unknown. Here, we combined a multivariate lesion-symptom mapping and voxel-based morphometry approach to analyse the relationship between lesion patterns and grey matter volume and production rate in speech and singing tasks. Lesion patterns for spontaneous speech and cued repetition extended into frontal, temporal and parietal areas typically reported within the speech production network. Impairment in spontaneous singing was associated with damage to the left anterior-pos

SUBMITTER: Martinez-Molina N 

PROVIDER: S-EPMC8842683 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature