Plasticity in the developing brain: neurophysiological basis for lesion-induced motor reorganization.

ABSTRACT: The plasticity of the developing brain can be observed following injury to the motor cortex and/or corticospinal tracts, the most commonly injured brain area in the pre- or peri-natal period. Factors such as the timing of injury, lesion size and lesion location may affect a single hemisphere's ability to acquire bilateral motor representation. Bilateral motor representation of single hemisphere origin is most likely to occur if brain injury occurs before the age of 2 years; however, the link between injury aetiology, reorganization type and functional outcome is largely understudied. We performed a retrospective review to examine reorganized cortical motor maps identified through transcranial magnetic stimulation in a cohort of 52 patients. Subsequent clinical, anthropometric and demograph

SUBMITTER: Batschelett M 

PROVIDER: S-EPMC8842689 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature