Sex Differences in the Relation Between Subjective Memory Complaints, Impairments in Instrumental Activities of Daily Living, and Risk of Dementia.

ABSTRACT:

Background

Older people with subjective memory complaints (SMC) and Instrumental Activities of Daily Living impairments (IADL-I) have an increased risk of developing dementia. Previous reports suggest that the predictive value of SMC and IADL-I may differ between sexes, leaving possible consequences for personalized risk prediction and prognosis. However, none of these studies addressed the competing risk of death, which may substantially differ between sexes.

Objective

We investigated sex-differences in the association between IADL-I, SMC, and incident dementia and mortality as competing risk.

Methods

3,409 community-dwelling older people without dementia (mean age 74.3±2.5), were followed for 6.7 years (median). Baseline SMC were assessed using the 15-item Geriatric

SUBMITTER: Abdulrahman H 

PROVIDER: S-EPMC8842768 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature