Sociodemographic, Lifestyle, Physical, and Psychosocial Determinants of Cognitive Reserve.

ABSTRACT:

Background

Cognitive reserve aims to explain individual differences in the susceptibility to the functional impact of dementia in the presence of equal amount of neuropathological damage. It is thought to be shaped by a combination of innate individual differences and lifetime exposures. Which determinants are associated with cognitive reserve remains unknown.

Objective

The objective of this study was to investigate the associations of sociodemographic, lifestyle, physical, and psychosocial determinants with cognitive reserve, and potential sex differences.

Methods

This cross-sectional study included 4,309 participants from the Rotterdam Study (mean age 63.9±10.7) between 2006-2016. Participants completed five cognitive tests and a brain MRI-scan. Cognitive reserve wa

SUBMITTER: Zijlmans JL 

PROVIDER: S-EPMC8842775 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature