Germline and Somatic Tumor Testing in Epithelial Ovarian Cancer: ASCO Guideline.

ABSTRACT:

Purpose

To provide recommendations on genetic and tumor testing for women diagnosed with epithelial ovarian cancer based on available evidence and expert consensus.

Methods

A literature search and prospectively defined study selection criteria sought systematic reviews, meta-analyses, randomized controlled trials (RCTs), and comparative observational studies published from 2007 through 2019. Guideline recommendations were based on the review of the evidence.

Results

The systematic review identified 19 eligible studies. The evidence consisted of systematic reviews of observational data, consensus guidelines, and RCTs.

Recommendations

All women diagnosed with epithelial ovarian cancer should have germline genetic testing for BRCA1/2 and other ovarian cance

SUBMITTER: Konstantinopoulos PA 

PROVIDER: S-EPMC8842911 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature