Distribution of acetylcholinesterase (Ace-1^R) target-site G119S mutation and resistance to carbamates and organophosphates in Anopheles gambiae sensu lato populations from Cameroon.

ABSTRACT:

Background

Cameroon is considering the implementation of indoor residual spraying (IRS) as a complementary measure to control malaria in the context of high pyrethroid resistance in major malaria vectors. Non-pyrethroid insecticide classes such as organophosphates and carbamates may be utilized in IRS due to widespread pyrethroid resistance. However, the success of this strategy depends on good knowledge of the resistance status of malaria vectors to carbamates and organophosphates. Here, we assessed the susceptibility profile of Anopheles gambiae sensu lato with respect to carbamates and organophosphate and the distribution of the molecular mechanism underlying resistance to these insecticides.

Methods

Anopheles gambiae s.l. mosquitoes were collected from nine settings acro

SUBMITTER: Binyang AJ 

PROVIDER: S-EPMC8842952 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature