Non-motor Adverse Effects Avoided by Directional Stimulation in Parkinson's Disease: A Case Report.

ABSTRACT:

Introduction

Deep brain stimulation (DBS) is widely used for treatment of advanced, medication-refractory Parkinson's disease (PD). However, a significant proportion of patients may suffer adverse effects; up to 10% will present one or more transient or permanent neurobehavioral events.

Patient and methods

In our case study, a 44-year-old woman diagnosed with PD 6 years previously who was suffering from motor fluctuations, dyskinesia, and freezing of gait episodes was submitted for DBS and implanted with directional electrodes. Intraoperative local field potentials (LFPs) were recorded. After surgery, conventional monopolar revision was performed. Preoperative 3T MRI studies and postoperative 3D and X-ray data were integrated using the Guide DTI software application (Brainla

SUBMITTER: Alonso-Frech F 

PROVIDER: S-EPMC8843015 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature