Antibiofilm and anticancer activities of unripe and ripe Azadirachta indica (neem) seed extracts.

ABSTRACT:

Background

Antibiotic resistances of pathogens and breast cancer warrant the search for new alternative strategies. Phytoextracts can eradicate microbe-borne diseases as well as cancer with lower side effects compared to conventional antibiotics.

Aim

Unripe and ripe Azadirachta indica (neem) seed extracts were explored as potential antibiofilm and anticancer agents in combating multidrug-resistant infectious bacteria as well as anticancer agents against the MDR breast cancer cell lines.

Methods

Shed-dried neem seeds (both unripe and ripe) were pulverized and extracted using methanol. The chemical components were identified with FTIR and gas chromatography - mass spectrometry. Antibiofilm activity of neem seed extracts were assessed in terms of minimum biofilm inhibito

SUBMITTER: Guchhait KC 

PROVIDER: S-EPMC8843028 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature