Ontology highlight
ABSTRACT:
SUBMITTER: Sengupta T
PROVIDER: S-EPMC8843091 | biostudies-literature | 2021 Nov
REPOSITORIES: biostudies-literature
Sengupta Titas T Koonce Noelle L NL Vázquez-Martínez Nabor N Moyle Mark W MW Duncan Leighton H LH Emerson Sarah E SE Han Xiaofei X Shao Lin L Wu Yicong Y Santella Anthony A Fan Li L Bao Zhirong Z Mohler William A WA Shroff Hari H Colón-Ramos Daniel A DA
eLife 20211116
During development, neurites and synapses segregate into specific neighborhoods or layers within nerve bundles. The developmental programs guiding placement of neurites in specific layers, and hence their incorporation into specific circuits, are not well understood. We implement novel imaging methods and quantitative models to document the embryonic development of the <i>C. elegans</i> brain neuropil<i>,</i> and discover that differential adhesion mechanisms control precise placement of single ...[more]