Long-term effects of PM_2.5 components on incident dementia in the northeastern United States.

ABSTRACT: Growing evidence has linked long-term fine particulate matter (PM_2.5) exposure to neurological disorders. Less is known about the individual effects of PM_2.5 components. A population-based cohort study investigated the association between long-term (1-year average) exposure to PM_2.5 components and dementia incidence among the elderly population (age, ≥65 years) in the United States. We used data from the Medicare Chronic Conditions Warehouse and a high-resolution PM_2.5 components dataset of the northeastern United States (2000-2017). We identified dementia diagnoses from patients' hospital and medical insurance records and carried out Cox proportional hazards regression to investigate their association with PM_2.5 components. Among ∼2 m

SUBMITTER: Li J 

PROVIDER: S-EPMC8844282 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature